Gene Review:
SLC2A14 - solute carrier family 2 (facilitated...
Homo sapiens
Synonyms:
GLUT-14, GLUT14, GLUT3, Glucose transporter type 14, SLC2A3P3, ...
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High impact information on SLC2A14
- GLUT14 (SLC2A14) maps to chromosome 12p13.3 (17.1M), about 10 Mb upstream of GLUT3, with which it shares remarkable identity [1].
- In contrast to the expression of GLUT3 in many tissues, both isoforms of GLUT14 are specifically expressed in testis [1].
- Until now GLUT14 was thought to be a pseudogene [1].
- We have identified and cloned GLUT14, a novel member of the glucose transporter family [1].
Biological context of SLC2A14
- GLUT14 has two alternatively spliced forms; the shorter form of GLUT14 (GLUT14-S) consists of 10 exons and produces a 497-amino-acid protein that is 94.5% identical to GLUT3 [1].
Anatomical context of SLC2A14
References
- GLUT14, a duplicon of GLUT3, is specifically expressed in testis as alternative splice forms. Wu, X., Freeze, H.H. Genomics (2002) [Pubmed]
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