Gene Review:
SLC2A3 - solute carrier family 2 (facilitated...
Homo sapiens
Synonyms:
GLUT-3, GLUT3, Glucose transporter type 3, brain, Solute carrier family 2, facilitated glucose transporter member 3
Medina,
Meneses,
Vera,
Guzman,
Nualart,
Astuya,
García,
Kato,
Carvajal,
Pinto,
Owen,
Mobasheri,
Richardson,
Mobasheri,
Shakibaei,
Hoyland,
Heijnen,
Oorschot,
Sixma,
Slot,
James,
Kokk,
Veräjänkorva,
Laato,
Wu,
Tapfer,
Pöllänen,
von Wolff,
Ursel,
Hahn,
Steldinger,
Strowitzki,
Shikhman,
Brinson,
Valbracht,
Lotz,
Gaster,
Beck-Nielsen,
Schrøder,
Fu,
Maianu,
Melbert,
Garvey,
Hauguel-de Mouzon,
Challier,
Kacemi,
Caüzac,
Malek,
Girard,
- Hypoxia inducible factor-1 and facilitative glucose transporters GLUT1 and GLUT3: putative molecular components of the oxygen and glucose sensing apparatus in articular chondrocytes. Mobasheri, A., Richardson, S., Mobasheri, R., Shakibaei, M., Hoyland, J.A. Histol. Histopathol. (2005)
- Sustained hypoglycemia affects glucose transporter expression of human blood leukocytes. Korgun, E.T., Demir, R., Sedlmayr, P., Desoye, G., Arikan, G.M., Puerstner, P., Haeusler, M., Dohr, G., Skofitsch, G., Hahn, T. Blood Cells Mol. Dis. (2002)
- Regenerating human muscle fibres express GLUT3 protein. Gaster, M., Beck-Nielsen, H., Schrøder, H.D. Pflugers Arch. (2002)
- Immunolocalization of glucose transporter 1 and 3 in the placenta: application to cytodiagnosis of Papanicolaou smear. Sato, M., Nakamura, Y., Sogawa, T., Yang, Q., Taniguchi, T., Taniguchi, E., Kagiya, T., Nakamura, M., Mori, I., Kakudo, K. Diagn. Cytopathol. (2002)
- The ubiquitous glucose transporter GLUT-1 is a receptor for HTLV. Manel, N., Kim, F.J., Kinet, S., Taylor, N., Sitbon, M., Battini, J.L. Cell (2003)
- Decreased concentrations of GLUT1 and GLUT3 glucose transporters in the brains of patients with Alzheimer's disease. Simpson, I.A., Chundu, K.R., Davies-Hill, T., Honer, W.G., Davies, P. Ann. Neurol. (1994)
- Coexpression of glucose transporters and glucokinase in Xenopus oocytes indicates that both glucose transport and phosphorylation determine glucose utilization. Morita, H., Yano, Y., Niswender, K.D., May, J.M., Whitesell, R.R., Wu, L., Printz, R.L., Granner, D.K., Magnuson, M.A., Powers, A.C. J. Clin. Invest. (1994)
- Thrombin stimulates glucose transport in human platelets via the translocation of the glucose transporter GLUT-3 from alpha-granules to the cell surface. Heijnen, H.F., Oorschot, V., Sixma, J.J., Slot, J.W., James, D.E. J. Cell Biol. (1997)
- Identification of hypoxically inducible mRNAs in HeLa cells using differential-display PCR. Role of hypoxia-inducible factor-1. O'Rourke, J.F., Pugh, C.W., Bartlett, S.M., Ratcliffe, P.J. Eur. J. Biochem. (1996)
- Dehydroascorbate transport in human chondrocytes is regulated by hypoxia and is a physiologically relevant source of ascorbic acid in the joint. McNulty, A.L., Stabler, T.V., Vail, T.P., McDaniel, G.E., Kraus, V.B. Arthritis Rheum. (2005)
- Human facilitative glucose transporters. Isolation, functional characterization, and gene localization of cDNAs encoding an isoform (GLUT5) expressed in small intestine, kidney, muscle, and adipose tissue and an unusual glucose transporter pseudogene-like sequence (GLUT6). Kayano, T., Burant, C.F., Fukumoto, H., Gould, G.W., Fan, Y.S., Eddy, R.L., Byers, M.G., Shows, T.B., Seino, S., Bell, G.I. J. Biol. Chem. (1990)
- QLS motif in transmembrane helix VII of the glucose transporter family interacts with the C-1 position of D-glucose and is involved in substrate selection at the exofacial binding site. Seatter, M.J., De la Rue, S.A., Porter, L.M., Gould, G.W. Biochemistry (1998)
- Glucose transporter expression in human skeletal muscle fibers. Gaster, M., Handberg, A., Beck-Nielsen, H., Schroder, H.D. Am. J. Physiol. Endocrinol. Metab. (2000)
- Glucose uptake via glucose transporter 3 by human platelets is regulated by protein kinase B. Ferreira, I.A., Mocking, A.I., Urbanus, R.T., Varlack, S., Wnuk, M., Akkerman, J.W. J. Biol. Chem. (2005)
- Constitutive activation of protein kinase B alpha by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Hajduch, E., Alessi, D.R., Hemmings, B.A., Hundal, H.S. Diabetes (1998)
- Cytokine regulation of facilitated glucose transport in human articular chondrocytes. Shikhman, A.R., Brinson, D.C., Valbracht, J., Lotz, M.K. J. Immunol. (2001)
- The GLUT3 glucose transporter isoform is differentially expressed within human placental cell types. Hauguel-de Mouzon, S., Challier, J.C., Kacemi, A., Caüzac, M., Malek, A., Girard, J. J. Clin. Endocrinol. Metab. (1997)
- Intracellular organization of insulin signaling and GLUT4 translocation. Watson, R.T., Pessin, J.E. Recent Prog. Horm. Res. (2001)
- Glucose transporter isoforms GLUT1 and GLUT3 transport dehydroascorbic acid. Rumsey, S.C., Kwon, O., Xu, G.W., Burant, C.F., Simpson, I., Levine, M. J. Biol. Chem. (1997)
- Glucose transporter proteins (GLUT) in human endometrium: expression, regulation, and function throughout the menstrual cycle and in early pregnancy. von Wolff, M., Ursel, S., Hahn, U., Steldinger, R., Strowitzki, T. J. Clin. Endocrinol. Metab. (2003)
- Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation. Fu, Y., Maianu, L., Melbert, B.R., Garvey, W.T. Blood Cells Mol. Dis. (2004)
- Estrogen and progesterone up-regulate glucose transporter expression in ZR-75-1 human breast cancer cells. Medina, R.A., Meneses, A.M., Vera, J.C., Guzman, C., Nualart, F., Astuya, A., García, M.A., Kato, S., Carvajal, A., Pinto, M., Owen, G.I. Endocrinology (2003)
- Kinetic analysis of the liver-type (GLUT2) and brain-type (GLUT3) glucose transporters in Xenopus oocytes: substrate specificities and effects of transport inhibitors. Colville, C.A., Seatter, M.J., Jess, T.J., Gould, G.W., Thomas, H.M. Biochem. J. (1993)
- Hexose transporters GLUT1 and GLUT3 are colocalized with hexokinase I in caveolae microdomains of rat spermatogenic cells. Rauch, M.C., Ocampo, M.E., Bohle, J., Amthauer, R., Yáñez, A.J., Rodríguez-Gil, J.E., Slebe, J.C., Reyes, J.G., Concha, I.I. J. Cell. Physiol. (2006)
- Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins. Burant, C.F., Bell, G.I. Biochemistry (1992)
- Involvement of the GLUT 3 transporter in myogenic regulation. Broydell, M., Mazzuca, D.M., Abidi, F., Kudo, P.A., Lo, T.C. Biochem. Mol. Biol. Int. (1997)
- Serotonin (5-Hydroxytryptamine), a novel regulator of glucose transport in rat skeletal muscle. Hajduch, E., Rencurel, F., Balendran, A., Batty, I.H., Downes, C.P., Hundal, H.S. J. Biol. Chem. (1999)
- Expression of insulin receptor substrates 1-3, glucose transporters GLUT-1-4, signal regulatory protein 1alpha, phosphatidylinositol 3-kinase and protein kinase B at the protein level in the human testis. Kokk, K., Veräjänkorva, E., Laato, M., Wu, X.K., Tapfer, H., Pöllänen, P. Anatomical science international / Japanese Association of Anatomists. (2005)
- Expression of facilitative glucose transporter isoforms in lung carcinomas: its relation to histologic type, differentiation grade, and tumor stage. Ito, T., Noguchi, Y., Satoh, S., Hayashi, H., Inayama, Y., Kitamura, H. Mod. Pathol. (1998)
- Molecular characterization and partial cDNA cloning of facilitative glucose transporters expressed in human articular chondrocytes; stimulation of 2-deoxyglucose uptake by IGF-I and elevated MMP-2 secretion by glucose deprivation. Richardson, S., Neama, G., Phillips, T., Bell, S., Carter, S.D., Moley, K.H., Moley, J.F., Vannucci, S.J., Mobasheri, A. Osteoarthr. Cartil. (2003)
- Distribution of the glucose transporters in human brain tumors. Nishioka, T., Oda, Y., Seino, Y., Yamamoto, T., Inagaki, N., Yano, H., Imura, H., Shigemoto, R., Kikuchi, H. Cancer Res. (1992)
- Expression of human glucose transporters in Xenopus oocytes: kinetic characterization and substrate specificities of the erythrocyte, liver, and brain isoforms. Gould, G.W., Thomas, H.M., Jess, T.J., Bell, G.I. Biochemistry (1991)