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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

yopB  -  translocator YopB

Yersinia enterocolitica

 
 
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High impact information on yopB

  • No YopE or YopH protein were observed within HeLa cells infected with the yopB mutant strain, suggesting that the loss of virulence of the mutant strain was due to its inability to translocate Yop effector proteins through the target cell plasma membrane [1].
  • Complementation experiments showed that the mutation was not polar with regard to yopB and yopD [2].

References

  1. The YopB protein of Yersinia pseudotuberculosis is essential for the translocation of Yop effector proteins across the target cell plasma membrane and displays a contact-dependent membrane disrupting activity. Håkansson, S., Schesser, K., Persson, C., Galyov, E.E., Rosqvist, R., Homblé, F., Wolf-Watz, H. EMBO J. (1996) [Pubmed]
  2. The Yersinia Yop virulon: LcrV is required for extrusion of the translocators YopB and YopD. Sarker, M.R., Neyt, C., Stainier, I., Cornelis, G.R. J. Bacteriol. (1998) [Pubmed]
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