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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ati  -  encodes the A-type inclusion protein

Cowpox virus

 
 
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Disease relevance of ati

 

High impact information on ati

  • Results presented here suggest that most of the ati gene is deleted in the VBH genome [1].
  • This suggests that ati mRNA 3' end formation involves cleavage of a late transcript, with subsequent 3' polyadenylation of the 5' cleavage product [2].
 

Analytical, diagnostic and therapeutic context of ati

  • In this study, sequence analysis of cDNAs of the 3' ends of ati mRNAs showed these mRNAs are 3' polyadenylated at the RNA cleavage site [2].

References

  1. Belo Horizonte virus: a vaccinia-like virus lacking the A-type inclusion body gene isolated from infected mice. Trindade, G.S., da Fonseca, F.G., Marques, J.T., Diniz, S., Leite, J.A., De Bodt, S., Van der Peer, Y., Bonjardim, C.A., Ferreira, P.C., Kroon, E.G. J. Gen. Virol. (2004) [Pubmed]
  2. A 43-nucleotide RNA cis-acting element governs the site-specific formation of the 3' end of a poxvirus late mRNA. Howard, S.T., Ray, C.A., Patel, D.D., Antczak, J.B., Pickup, D.J. Virology (1999) [Pubmed]
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