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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

CTVgp11  -  23-kDa protein

Citrus tristeza virus

 
 
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Disease relevance of CTVgp11

 

High impact information on CTVgp11

  • Three additional polypeptides, with estimated sizes of 21 kDa, 23 kDa and 27 kDa, were translated from a range of RNA molecules smaller than 3.2 kb [2].
  • The 3' proximal open reading frame (ORF 11) in the citrus tristeza virus (CTV) genome potentially encodes a protein of 209 amino acids with an estimated molecular weight of 23 kDa (p23) [3].
 

Analytical, diagnostic and therapeutic context of CTVgp11

  • Using these antisera on a Western blot, a protein of expected size (23 kDa) was detected in tissue extracts from CTV-infected citrus but not from uninfected citrus [3].

References

  1. The 23-kDa protein coded by the 3'-terminal gene of citrus tristeza virus is an RNA-binding protein. López, C., Navas-Castillo, J., Gowda, S., Moreno, P., Flores, R. Virology (2000) [Pubmed]
  2. Populations of citrus tristeza virus contain smaller-than-full-length particles which encapsidate sub-genomic RNA molecules. Mawassi, M., Gafny, R., Gagliardi, D., Bar-Joseph, M. J. Gen. Virol. (1995) [Pubmed]
  3. Characterization of the 3' proximal gene of the citrus tristeza closterovirus genome. Pappu, S.S., Febres, V.J., Pappu, H.R., Lee, R.F., Niblett, C.L. Virus Res. (1997) [Pubmed]
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