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Gene Review

Hoxd8  -  homeobox D8

Mus musculus

Synonyms: 4921540P06Rik, AI047735, Homeobox protein Hox-4.3, Homeobox protein Hox-5.4, Homeobox protein Hox-D8, ...
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High impact information on Hoxd8

  • The phenotype of Hoxd8 loss-of-function mutants is presented, and compared with that of Hoxb8- and Hoxc8-null mice [1].
  • Like other genes of the HOX-4(5) complex, Hox-4.3 is expressed in developing limbs and gonads, suggesting that 'cluster specificity' could be a feature of the HOX network [2].
  • Primary structure and embryonic expression pattern of the mouse Hox-4.3 homeobox gene [2].

Anatomical context of Hoxd8


  1. Axial skeletal patterning in mice lacking all paralogous group 8 Hox genes. van den Akker, E., Fromental-Ramain, C., de Graaff, W., Le Mouellic, H., Brûlet, P., Chambon, P., Deschamps, J. Development (2001) [Pubmed]
  2. Primary structure and embryonic expression pattern of the mouse Hox-4.3 homeobox gene. Izpisùa-Belmonte, J.C., Dollé, P., Renucci, A., Zappavigna, V., Falkenstein, H., Duboule, D. Development (1990) [Pubmed]
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