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Gene Review

dyb-1  -  Protein DYB-1

Caenorhabditis elegans

 
 
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Disease relevance of dyb-1

 

High impact information on dyb-1

 

Biological context of dyb-1

  • Mutations of dyb-1 and dys-1 lead to similar phenotypes, comprising hyperactivity and a tendency to hypercontract, which suggest that these proteins may participate in a common function [3].
  • Dystrophin, dystrobrevin, dystroglycans and several sarcoglycans have conserved homologues in the genome of C. elegans [4].
 

Physical interactions of dyb-1

  • These results are consistent with a model according to which dystrobrevin must bind to dystrophin to be able to function properly [5].
 

Analytical, diagnostic and therapeutic context of dyb-1

References

 
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