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Gene Review:

dyc-1 - Protein DYC-1

Caenorhabditis elegans

Gieseler, K. et al., Grisoni, K. et al., Giugia, J. et al.

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High impact information on dyc-1

Since Caenorhabditis elegans possesses a dystrophin-like gene (dys-1), we investigated whether homologues of the DGC members could also be found in the C. elegans genome [1].
Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans [2].
Mutations in the dystrophin-like dys-1 gene of Caenorhabditis elegans result in reduced acetylcholinesterase activity [3].

References

Genetic evidence for a dystrophin-glycoprotein complex (DGC) in Caenorhabditis elegans. Grisoni, K., Martin, E., Gieseler, K., Mariol, M.C., Ségalat, L. Gene (2002) [Pubmed]
Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans. Gieseler, K., Bessou, C., Ségalat, L. Neurogenetics (1999) [Pubmed]
Mutations in the dystrophin-like dys-1 gene of Caenorhabditis elegans result in reduced acetylcholinesterase activity. Giugia, J., Gieseler, K., Arpagaus, M., Ségalat, L. FEBS Lett. (1999) [Pubmed]

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