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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

glh-1  -  Protein GLH-1

Caenorhabditis elegans

 
 
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High impact information on glh-1

  • Injection of antisense glh-1 or glh-2 RNA into wild-type worms causes some offspring to develop into sterile adults, suggesting that either or both genes are required for normal germ-line development [1].
  • glh-1, a germ-line putative RNA helicase from Caenorhabditis, has four zinc fingers [2].
  • However, unlike all other putative RNA helicases, glh-1 also contains four retroviral-type zinc fingers [2].
  • The amino terminus of the predicted protein of glh-1 contains a set of glycine-rich repeats similar in location and sequence to those in the predicted vasa protein [2].

References

  1. Multiple potential germ-line helicases are components of the germ-line-specific P granules of Caenorhabditis elegans. Gruidl, M.E., Smith, P.A., Kuznicki, K.A., McCrone, J.S., Kirchner, J., Roussell, D.L., Strome, S., Bennett, K.L. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  2. glh-1, a germ-line putative RNA helicase from Caenorhabditis, has four zinc fingers. Roussell, D.L., Bennett, K.L. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]
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