Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

spk-1 - Protein SPK-1

Caenorhabditis elegans

Kuroyanagi, H. et al., Longman, D. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on spk-1

RNAi with CeSRPK, an SR protein kinase, resulted in early embryonic lethality, suggesting an essential role for SR protein phosphorylation during development [1].
Both spk-1 and CeSF2 are predominantly expressed in germlines [2].
SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development [2].

Biological context of spk-1

RNA interference (RNAi) experiments revealed that spk-1 and CeSF2 play an essential role at the embryonic stage of C. elegans [2].

References

Functional characterization of SR and SR-related genes in Caenorhabditis elegans. Longman, D., Johnstone, I.L., Cáceres, J.F. EMBO J. (2000) [Pubmed]
SPK-1, a C. elegans SR protein kinase homologue, is essential for embryogenesis and required for germline development. Kuroyanagi, H., Kimura, T., Wada, K., Hisamoto, N., Matsumoto, K., Hagiwara, M. Mech. Dev. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

SRPK3	Bos taurus
SRPK3	Canis lupus familiaris
srpk3	Danio rerio
SRPK3	Homo sapiens
SRPK3	Macaca mulatta
Srpk3	Mus musculus
SRPK3	Pan troglodytes
Srpk3	Rattus norvegicus
srpk2	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.