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Gene Review

tbx-9  -  Protein TBX-9

Caenorhabditis elegans

 
 
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High impact information on Brachyury

  • Inhibiting tbx-9 alone using RNA interference (RNAi) produces worms that have a thickened, 'bobbed tail' phenotype, similar to that seen in mutants of vab-7, which itself has been shown to pattern posterior muscle and hypodermal cells [1].
  • Conservation of Brachyury, Mef2, and Snail in the myogenic lineage of jellyfish: a connection to the mesoderm of bilateria [2].
  • The expression pattern of tbx-8 is markedly similar to that of tbx-9 [3].
  • A pair of homologous T-box transcription factors (tbx-8 and tbx-9) is found to interact in both C. elegans and C. briggsae, indicating that their compensatory function is conserved [4].

References

 
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