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Gene Review

skr-7  -  Protein SKR-7

Caenorhabditis elegans

 
 
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High impact information on skr-7

  • First, the highly similar skr-7, -8, -9, and -10 genes are required for posterior body morphogenesis, embryonic and larval development, and cell proliferation [1].
  • Suppression of skr-1 or skr-2 genes by double-stranded RNA interference resulted in embryonic death, whereas that of skr-7, -8, -9, or -10 was associated with slow growth and morphological abnormalities [2].

References

  1. The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis. Nayak, S., Santiago, F.E., Jin, H., Lin, D., Schedl, T., Kipreos, E.T. Curr. Biol. (2002) [Pubmed]
  2. Multiple Skp1-related proteins in Caenorhabditis elegans: diverse patterns of interaction with Cullins and F-box proteins. Yamanaka, A., Yada, M., Imaki, H., Koga, M., Ohshima, Y., Nakayama, K. Curr. Biol. (2002) [Pubmed]
 
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