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Gene Review:

skr-1 - Protein SKR-1

Caenorhabditis elegans

Yamanaka, A. et al., Nayak, S. et al.

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High impact information on skr-1

Suppression of skr-1 or skr-2 genes by double-stranded RNA interference resulted in embryonic death, whereas that of skr-7, -8, -9, or -10 was associated with slow growth and morphological abnormalities [1].
Second, the related skr-1 and -2 genes are required for the restraint of cell proliferation, progression through the pachytene stage of meiosis, and the formation of bivalent chromosomes at diakinesis [2].

References

Multiple Skp1-related proteins in Caenorhabditis elegans: diverse patterns of interaction with Cullins and F-box proteins. Yamanaka, A., Yada, M., Imaki, H., Koga, M., Ohshima, Y., Nakayama, K. Curr. Biol. (2002) [Pubmed]
The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell proliferation, morphogenesis, and meiosis. Nayak, S., Santiago, F.E., Jin, H., Lin, D., Schedl, T., Kipreos, E.T. Curr. Biol. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP008719	Anopheles gambiae str. PEST
AGOS_ADR295C	Ashbya gossypii ATCC 10895
SKP1	Bos taurus
skr-2	Caenorhabditis elegans
SKP1	Canis lupus familiaris
skp1	Danio rerio
skpA	Drosophila melanogaster
SKP1	Gallus gallus
SKP1	Homo sapiens
KLLA0E16941g	Kluyveromyces lactis NRRL Y-1140
LOC703550	Macaca mulatta
MGG_04978	Magnaporthe oryzae 70-15
Skp1a	Mus musculus
NCU08991	Neurospora crassa OR74A
Os11g0456300	Oryza sativa Japonica Group
SKP1	Pan troglodytes
Skp1	Rattus norvegicus
SKP1	Saccharomyces cerevisiae S288c
skp1	Schizosaccharomyces pombe 972h-
skp1	Xenopus (Silurana) tropicalis

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