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Gene Review

gsnl-1  -  Protein GSNL-1

Caenorhabditis elegans

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High impact information on gelsolin

  • In these highly conserved genes, two previously known gene families have been brought together, families encoding the actin-binding proteins related to gelsolin and the leucine-rich-repeat (LRR) group of proteins involved in protein-protein interactions [1].
  • Some of the residues considered essential for actin and calcium binding in gelsolin S1 and villin V1 are also well conserved [2].
  • The gene encodes a single transcript encoding a protein consisting of a leucine-rich amino terminal half and a carboxyterminal half with high sequence similarity to gelsolin [2].

Biological context of gelsolin


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