Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

gap-1 - Protein GAP-1

Caenorhabditis elegans

Hajnal, A. et al., Chen, W. et al.

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High impact information on gap-1

A loss-of-function mutation in gap-1 suppresses the vulvaless phenotype of mutations in the let-60 ras signaling pathway, but a gap-1 single mutant does not exhibit excess vulval induction [1].
Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase [1].
CeGAP is therefore the first GTPase-activating protein acting on Ras-related proteins across different subfamilies [2].

References

Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase. Hajnal, A., Whitfield, C.W., Kim, S.K. Genes Dev. (1997) [Pubmed]
Characterization of a promiscuous GTPase-activating protein that has a Bcr-related domain from Caenorhabditis elegans. Chen, W., Blanc, J., Lim, L. J. Biol. Chem. (1994) [Pubmed]

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