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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ser-1  -  Protein SER-1

Caenorhabditis elegans

 
 
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High impact information on ser-1

  • In contrast, mpz-1 RNAi has no effect on 5-HT stimulated egg-laying in ser-1 mutants rescued by expression of a truncated SER-1 that lacks the C-terminal PDZ binding motif [1].
  • Loss of mod-1 function in males also produces defects in ventral tail curling and enhances the turning defects in ser-1 mutant males [2].

References

  1. SER-1, a Caenorhabditis elegans 5-HT(2)-like receptor, and a multi-PDZ domain containing protein (MPZ-1) interact in vulval muscle to facilitate serotonin-stimulated egg-laying. Xiao, H., Hapiak, V.M., Smith, K.A., Lin, L., Hobson, R.J., Plenefisch, J., Komuniecki, R. Dev. Biol. (2006) [Pubmed]
  2. The G-protein-coupled serotonin receptor SER-1 regulates egg laying and male mating behaviors in Caenorhabditis elegans. Carnell, L., Illi, J., Hong, S.W., McIntire, S.L. J. Neurosci. (2005) [Pubmed]
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