Gene Review:
Htr2a - 5-hydroxytryptamine (serotonin) receptor...
Rattus norvegicus
Synonyms:
5-HT-2, 5-HT-2A, 5-HT2A, 5-hydroxytryptamine receptor 2A, 5Ht-2, ...
- Evidence that m-chlorophenylpiperazine-induced hyperthermia in rats is mediated by stimulation of 5-HT2C receptors. Mazzola-Pomietto, P., Aulakh, C.S., Wozniak, K.M., Murphy, D.L. Psychopharmacology (Berl.) (1996)
- Contribution of the peripheral 5-HT 2A receptor to mechanical hyperalgesia in a rat model of neuropathic pain. Nitanda, A., Yasunami, N., Tokumo, K., Fujii, H., Hirai, T., Nishio, H. Neurochem. Int. (2005)
- Comparative involvement of 5-HT1, 5-HT2 and 5-HT3 receptors in stress-induced colonic motor alterations in rats. Gué, M., Alary, C., Rio-Lacheze, C.D., Junien, J.L., Buéno, L. Eur. J. Pharmacol. (1993)
- Signal transduction pathways responsible for serotonin-mediated prostaglandin G/H synthase expression in rat mesangial cells. Stroebel, M., Goppelt-Struebe, M. J. Biol. Chem. (1994)
- Role of 5-hydroxytryptamine in intestinal water and electrolyte movement during gut anaphylaxis. Mourad, F.H., O'Donnell, L.J., Ogutu, E., Dias, J.A., Farthing, M.J. Gut (1995)
- Cross-tolerance studies of serotonin receptors involved in behavioral effects of LSD in rats. Krebs, K.M., Geyer, M.A. Psychopharmacology (Berl.) (1994)
- Activation of 5-HT2A receptors impairs response control of rats in a five-choice serial reaction time task. Koskinen, T., Ruotsalainen, S., Puumala, T., Lappalainen, R., Koivisto, E., Männistö, P.T., Sirviö, J. Neuropharmacology (2000)
- Biochemical and pharmacological properties of SR 46349B, a new potent and selective 5-hydroxytryptamine2 receptor antagonist. Rinaldi-Carmona, M., Congy, C., Santucci, V., Simiand, J., Gautret, B., Neliat, G., Labeeuw, B., Le Fur, G., Soubrie, P., Breliere, J.C. J. Pharmacol. Exp. Ther. (1992)
- Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT. Gozlan, H., El Mestikawy, S., Pichat, L., Glowinski, J., Hamon, M. Nature (1983)
- Serotonin regulates rhythmic whisking. Hattox, A., Li, Y., Keller, A. Neuron (2003)
- 5-HT2 and 5-HT3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat. Beubler, E., Horina, G. Gastroenterology (1990)
- Ketanserin: a selective antagonist of 5-HT2 serotoninergic receptors. Van Nueten, J.M., Leysen, J.E., Schuurkes, J.A., Vanhoutte, P.M. Lancet (1983)
- Cloning and functional characterization of the rat stomach fundus serotonin receptor. Foguet, M., Hoyer, D., Pardo, L.A., Parekh, A., Kluxen, F.W., Kalkman, H.O., Stühmer, W., Lübbert, H. EMBO J. (1992)
- Evidence that 1-(2,5-dimethoxy-4-methylphenyl)-2-aminopropane-induced hypophagia and hyperthermia in rats is mediated by serotonin-2A receptors. Aulakh, C.S., Mazzola-Pomietto, P., Wozniak, K.M., Hill, J.L., Murphy, D.L. J. Pharmacol. Exp. Ther. (1994)
- Evidence that 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-induced hyperthermia in rats is mediated by stimulation of 5-HT2A receptors. Mazzola-Pomietto, P., Aulakh, C.S., Wozniak, K.M., Hill, J.L., Murphy, D.L. Psychopharmacology (Berl.) (1995)
- Evidence for the involvement of central 5-HT1A receptors in the mediation of lordosis behavior in the female rat. Ahlenius, S., Larsson, K., Fernandez-Guasti, A. Psychopharmacology (Berl.) (1989)
- Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3,4-methylenedioxymethamphetamine. Nash, J.F., Meltzer, H.Y., Gudelsky, G.A. J. Pharmacol. Exp. Ther. (1988)
- Isolation and characterization of the rat 5-hydroxytryptamine type 2 receptor promoter: constitutive and inducible activity in myometrial smooth muscle cells. Du, Y.L., Wilcox, B.D., Teitler, M., Jeffrey, J.J. Mol. Pharmacol. (1994)
- Evidence for involvement of 5-HT1C and 5-HT2 receptors in the food intake suppressant effects of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI). Aulakh, C.S., Hill, J.L., Yoney, H.T., Murphy, D.L. Psychopharmacology (Berl.) (1992)
- Serotonin 5-hydroxytryptamine 2A receptor-coupled phospholipase C and phospholipase A2 signaling pathways have different receptor reserves. Kurrasch-Orbaugh, D.M., Watts, V.J., Barker, E.L., Nichols, D.E. J. Pharmacol. Exp. Ther. (2003)
- Serotonin-dependent collagenase induction in rat myometrial smooth muscle cells: mediation by the 5-HT2 receptor. Rydelek-Fitzgerald, L., Wilcox, B.D., Teitler, M., Jeffrey, J.J. Mol. Cell. Endocrinol. (1993)
- Induction and maintenance of ganglionic long-term potentiation require activation of 5-hydroxytryptamine (5-HT3) receptors. Alkadhi, K.A., Salgado-Commissariat, D., Hogan, Y.H., Akpaudo, S.B. J. Physiol. (Lond.) (1996)
- Modulation by 5-HT1A receptors of the 5-HT2 receptor-mediated tachykinin-induced contraction of the rat trachea in vitro. Germonpré, P.R., Joos, G.F., Pauwels, R.A. Br. J. Pharmacol. (1998)
- Functional study of rat 5-HT2A receptors using antisense oligonucleotides. Van Oekelen, D., Megens, A., Meert, T., Luyten, W.H., Leysen, J.E. J. Neurochem. (2003)
- Transient and long-lasting actions of 5-HT on rat dentate gyrus neurones in vitro. Piguet, P., Galvan, M. J. Physiol. (Lond.) (1994)
- Ketanserin analogues: the effect of structural modification on 5-HT2 serotonin receptor binding. Ismaiel, A.M., Arruda, K., Teitler, M., Glennon, R.A. J. Med. Chem. (1995)
- Irreversible blockade of central 5-HT1A receptor binding sites by the photoaffinity probe 8-methoxy-3'-NAP-amino-PAT. Emerit, M.B., Gozlan, H., Marquet, A., Hamon, M. Eur. J. Pharmacol. (1986)
- Effect of repeated treatment with electroconvulsive shock (ECS) on serotonin receptor density and turnover in the rat cerebral cortex. Nowak, G., Dulinski, J. Pharmacol. Biochem. Behav. (1991)
- Cloning, functional expression and role in cell growth regulation of a hamster 5-HT2 receptor subtype. Van Obberghen-Schilling, E., Vouret-Craviari, V., Haslam, R.J., Chambard, J.C., Pouysségur, J. Mol. Endocrinol. (1991)
- Metabotropic glutamate receptor in C6BU-1 glioma cell has NMDA receptor-ion channel complex-like properties and interacts with serotonin2 receptor-stimulated signal transduction. Shinno, H., Mikuni, M., Saitoh, K., Tomita, U., Yamawaki, S., Takahashi, K. J. Neurochem. (1994)
- Selective heterologous regulation of 5-HT1A receptor-stimulated 35S GTPgammaS binding in the anterior cingulate cortex as a result of 5-HT2 receptor activation. Valdez, M., Burke, T.F., Hensler, J.G. Brain Res. (2002)
- Activation of Erk mitogen-activated protein kinase proteins by vascular serotonin receptors. Watts, S.W., Yang, P., Banes, A.K., Baez, M. J. Cardiovasc. Pharmacol. (2001)
- GR43175, a selective agonist for the 5-HT1-like receptor in dog isolated saphenous vein. Humphrey, P.P., Feniuk, W., Perren, M.J., Connor, H.E., Oxford, A.W., Coates, L.H., Butina, D. Br. J. Pharmacol. (1988)
- Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration. Chlan-Fourney, J., Ashe, P., Nylen, K., Juorio, A.V., Li, X.M. Brain Res. (2002)
- Subchronic treatment with anxiolytic doses of the 5-HT1A receptor agonist ipsapirone does not affect 5-HT2 receptor sensitivity in the rat. Baudrie, V., De Vry, J., Broqua, P., Schmidt, B., Chaouloff, F., Glaser, T. Eur. J. Pharmacol. (1993)
- 5-HT1A, 5-HT2, and GABAB receptors interact to modulate neurotransmitter release probability in layer 2/3 somatosensory rat cortex as evaluated by the paired pulse protocol. Torres-Escalante, J.L., Barral, J.A., Ibarra-Villa, M.D., Pérez-Burgos, A., Góngora-Alfaro, J.L., Pineda, J.C. J. Neurosci. Res. (2004)
- Influence of catecholaminergic and serotonergic receptor antagonists on the hyperglycaemic response to the neuroglucopaenic agent, 2-deoxy-D-glucose. Baudrie, V., Chaouloff, F. Neuropharmacology (1991)
- Unique expression patterns of 5-HT2A and 5-HT2C receptors in the rat brain during postnatal development: Western blot and immunohistochemical analyses. Li, Q.H., Nakadate, K., Tanaka-Nakadate, S., Nakatsuka, D., Cui, Y., Watanabe, Y. J. Comp. Neurol. (2004)
- Different serotonin receptor types participate in 5-hydroxytryptophan-induced gonadotropins and prolactin release in the female infantile rat. Lacau-Mengido, I.M., Libertun, C., Becú-Villalobos, D. Neuroendocrinology (1996)
- 5-HT and carbohydrate suppression: effects of 5-HT antagonists on the action of d-fenfluramine and DOI. Lawton, C.L., Blundell, J.E. Pharmacol. Biochem. Behav. (1993)
- Cardiovascular effects of 5HT2 and 5HT3 receptor stimulation in the nucleus tractus solitarius of spontaneously hypertensive rats. Merahi, N., Laguzzi, R. Brain Res. (1995)
- Role of striatal serotonin2A and serotonin2C receptor subtypes in the control of in vivo dopamine outflow in the rat striatum. Lucas, G., Spampinato, U. J. Neurochem. (2000)