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Gene Review:

ECH1 - enoyl CoA hydratase 1, peroxisomal

Homo sapiens

Synonyms: Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial, HPXEL

Kovalyov, L.I. et al., FitzPatrick, D.R. et al., de Boer, V.C. et al.

Kovalyov, Kovalyova, Kovalyov, Serebryakova, Moshkovskii, Shishkin,

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High impact information on ECH1

Up-regulation of genes (Hmgcs2, Ech1, Acox1, Pcca, Lpl and Acaa2) was verified and confirmed by quantitative real time PCR [1].
We have also identified human ECH1 cDNA and mapped its structural gene to 19q13, 3' to the ryanodine receptor, by hybridization to somatic cell hybrid DNA and chromosome 19-specific cosmid arrays [2].
Polymorphism of Delta3,5-Delta2,4-Dienoyl-Coenzyme A Isomerase (the ECH1 Gene Product Protein) in Human Striated Muscle Tissue [3].
Two polymorphic variants of the ECH1 gene product protein (Delta3,5-Delta2,4-dienoyl-coenzyme A isomerase) have been revealed by proteomics methods in samples of human striated muscle tissue [3].

References

Chronic quercetin exposure affects fatty acid catabolism in rat lung. de Boer, V.C., van Schothorst, E.M., Dihal, A.A., van der Woude, H., Arts, I.C., Rietjens, I.M., Hollman, P.C., Keijer, J. Cell. Mol. Life Sci. (2006) [Pubmed]
Isolation and characterization of rat and human cDNAs encoding a novel putative peroxisomal enoyl-CoA hydratase. FitzPatrick, D.R., Germain-Lee, E., Valle, D. Genomics (1995) [Pubmed]
Polymorphism of Delta3,5-Delta2,4-Dienoyl-Coenzyme A Isomerase (the ECH1 Gene Product Protein) in Human Striated Muscle Tissue. Kovalyov, L.I., Kovalyova, M.A., Kovalyov, P.L., Serebryakova, M.V., Moshkovskii, S.A., Shishkin, S.S. Biochemistry Mosc. (2006) [Pubmed]

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AgaP_AGAP002661	Anopheles gambiae str. PEST
DCI1	Arabidopsis thaliana
ECH1	Bos taurus
F58A6.1	Caenorhabditis elegans
Y25C1A.13	Caenorhabditis elegans
ECH1	Canis lupus familiaris
ech1	Danio rerio
CG9577	Drosophila melanogaster
ECH1	Gallus gallus
ECH1	Macaca mulatta
MGG_07309	Magnaporthe oryzae 70-15
Ech1	Mus musculus
NCU06647	Neurospora crassa OR74A
Os01g0925200	Oryza sativa Japonica Group
LOC747511	Pan troglodytes
Ech1	Rattus norvegicus
ech1	Xenopus (Silurana) tropicalis

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