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Gene Review:

Rnu2-10 - U2 small nuclear RNA 10

Mus musculus

Synonyms: Rnu2, nmf291

Patton, J.R. et al., Pruijn, G.J. et al., Sive, H.L. et al., Tani, T. et al.

Patton, Padgett,

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High impact information on Rnu2

Potential cellular binding sites include promoter elements of the histone H2B gene, the human interferon beta gene, the human and mouse immunoglobulin VK and VH genes and the mammal/chicken/Xenopus laevis U1 and U2 small nuclear RNA genes [1].
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes [2].
Caenorhabditis elegans pseudouridine synthase 1 activity in vivo: tRNA is a substrate, but not U2 small nuclear RNA [3].
In yeast, Pus1p has been shown to have dual substrate specificity, modifying uridines in tRNAs and at position 44 in U2 small nuclear RNA (U2 snRNA) [3].

Analytical, diagnostic and therapeutic context of Rnu2

Molecular cloning and characterization of a gene for rat U2 small nuclear RNA [4].

References

Nuclear factor III, a novel sequence-specific DNA-binding protein from HeLa cells stimulating adenovirus DNA replication. Pruijn, G.J., van Driel, W., van der Vliet, P.C. Nature (1986) [Pubmed]
Interaction of a common factor with conserved promoter and enhancer sequences in histone H2B, immunoglobulin, and U2 small nuclear RNA (snRNA) genes. Sive, H.L., Roeder, R.G. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
Caenorhabditis elegans pseudouridine synthase 1 activity in vivo: tRNA is a substrate, but not U2 small nuclear RNA. Patton, J.R., Padgett, R.W. Biochem. J. (2003) [Pubmed]
Molecular cloning and characterization of a gene for rat U2 small nuclear RNA. Tani, T., Watanabe-Nagasu, N., Okada, N., Ohshima, Y. J. Mol. Biol. (1983) [Pubmed]

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