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Gene Review:

Csta1 - cystatin A1

Mus musculus

Synonyms: Csta, Cystatin-A, Cystatin-A1, Stefin-A

Korolenko, T.A. et al., Hawley-Nelson, P. et al.

Korolenko, Poteryaeva, Falameeva, Levina,

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Disease relevance of Csta

The concentration of stefin A (cystatin A in mice) was measured in animals with experimental tumors (LS lymphosarcoma, HA-1-hepatoma, and Lewis lung carcinoma) during effective antitumor therapy [1].

High impact information on Csta

Regulation of expression of cystatin A in epidermis and tumors suggests that it may be important in the control of normal keratinocyte proliferation and differentiation and in malignant conversion [2].

Analytical, diagnostic and therapeutic context of Csta

Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis [2].

References

Cystein proteinase inhibitor stefin A as an indicator of efficiency of tumor treatment in mice. Korolenko, T.A., Poteryaeva, O.N., Falameeva, O.V., Levina, O.A. Bull. Exp. Biol. Med. (2003) [Pubmed]
Molecular cloning of mouse epidermal cystatin A and detection of regulated expression in differentiation and tumorigenesis. Hawley-Nelson, P., Roop, D.R., Cheng, C.K., Krieg, T.M., Yuspa, S.H. Mol. Carcinog. (1988) [Pubmed]

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