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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Tcte2  -  t-complex-associated testis expressed 2

Mus musculus

Synonyms: AI429268, Tcte-2
 
 
 
 
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High impact information on Tcte2

  • A deletion of the 5' part of the locus abolishes Tcte2 expression on the t haplotype form of chromosome 17 [1].
  • Tcte2 (t complex testes expressed 2) is a male meiosis-specific gene that maps to band 3.3 of mouse chromosome 17 [1].
  • The Tcte2 gene expresses a coding mRNA and a number of putative non-ORF transcripts in meiosis I [1].
  • The identification of polymorphisms in t haplotypes and in different mouse species allows alleles of Tcte2 to be proposed as candidates for loci which contribute to both meiotic drive and hybrid sterility phenotypes [1].

References

  1. Identification of a male meiosis-specific gene, Tcte2, which is differentially spliced in species that form sterile hybrids with laboratory mice and deleted in t chromosomes showing meiotic drive. Braidotti, G., Barlow, D.P. Dev. Biol. (1997) [Pubmed]
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