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Gene Review:

tor - tortured

Mus musculus

Yamamoto, K. et al., Nesper, J. et al.

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Disease relevance of tor

Characterization of Vibrio cholerae O1 El tor galU and galE mutants: influence on lipopolysaccharide structure, colonization, and biofilm formation [1].

High impact information on tor

These results suggest that the absence of fibrin in some tissues reflects ongoing local fibrinolysis, and that increases in plasminogen activator inhibitory and tissue fac- tor gene expression and decreases in urokinase-type plasminogen activator expression are necessary for tissue-specific fibrin deposition [2].

References

Characterization of Vibrio cholerae O1 El tor galU and galE mutants: influence on lipopolysaccharide structure, colonization, and biofilm formation. Nesper, J., Lauriano, C.M., Klose, K.E., Kapfhammer, D., Kraiss, A., Reidl, J. Infect. Immun. (2001) [Pubmed]
Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator. Yamamoto, K., Loskutoff, D.J. J. Clin. Invest. (1996) [Pubmed]

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