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Gene Review

JMJD1C  -  jumonji domain containing 1C

Homo sapiens

Synonyms: DKFZp761F0118, FLJ14374, JHDM2C, Jumonji domain-containing protein 1C, KIAA1380, ...
 
 
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Psychiatry related information on JMJD1C

  • Microsatellite marker D10S1225, associated with Alzheimer's disease, non-syndromic congenital retinal non-attachment (NCRNA) and non-syndromic autosomal recessive persistent hyperplastic primary vitreous (arPHPV), was located within the TRIP8-EGR2 locus [1].
 

High impact information on JMJD1C

 

Biological context of JMJD1C

  • Because JMJC domain proteins are implicated in chromatin remodeling, TRIP8 was predicted to be a transcriptional regulator associated with nuclear hormone receptors [1].
  • Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism [2].

References

  1. Identification and characterization of TRIP8 gene in silico. Katoh, M., Katoh, M. Int. J. Mol. Med. (2003) [Pubmed]
  2. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism. Castermans, D., Vermeesch, J.R., Fryns, J.P., Steyaert, J.G., Van de Ven, W.J., Creemers, J.W., Devriendt, K. Eur. J. Hum. Genet. (2007) [Pubmed]
 
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