Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

Smgc - submandibular gland protein C

Mus musculus

Synonyms: 2310010P21Rik, DXImx49e, Muc19, Sfc21, Submandibular gland protein C

Culp, D.J. et al., Zinzen, K.M. et al.

Culp, Latchney, Fallon, Denny, Denny, Couwenhoven, Chuang,

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High impact information on Smgc

Smgc is localized on rat chromosome 7q34-35 and on mouse chromosome 15E3, both immediately upstream of the high molecular weight salivary mucin, Muc19 [1].
Comparative Northern analyses between the major salivary glands demonstrate highly selective Muc19 expression in neonatal and adult sublingual glands, whereas Smgc is expressed in neonatal submandibular and sublingual glands [2].
Regulation of Muc19/Smgc gene expression is discussed with respect to alternative splicing and mucous cell cytodifferentiation [2].

References

Molecular cloning and characterization of the neonatal rat and mouse submandibular gland protein SMGC. Zinzen, K.M., Hand, A.R., Yankova, M., Ball, W.D., Mirels, L. Gene (2004) [Pubmed]
The gene encoding mouse Muc19: cDNA, genomic organization and relationship to Smgc. Culp, D.J., Latchney, L.R., Fallon, M.A., Denny, P.A., Denny, P.C., Couwenhoven, R.I., Chuang, S. Physiol. Genomics (2004) [Pubmed]

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