The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia
  • UniProt
  • Ensembl

Table of contents

About

Terms

 

Gene Review: 

Nox3  -  NADPH oxidase 3

Mus musculus

Synonyms: GP91-3, het, nmf250
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Nox3

  • Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase [1].
  • The present study used the C57BL6JEi-het mouse strain (het), which lacks macular otoconia, to elucidate the contribution of specific vestibular receptors [2].
  • Body mass and food intake were only slightly attenuated in the het mice, and percent body fat, after 8 weeks, was not different in the 2G het group [2].
  • The het mice lack otoconia, the inertial mass critical for natural stimulation of inner ear gravity receptors [3].
  • The C57BL/6JEi-het mouse may be an excellent model of gravity receptor sensory deprivation [3].
 

Biological context of Nox3

 

Analytical, diagnostic and therapeutic context of Nox3

  • In this study, eight het and eight WT mice were exposed to 2G for 8 weeks by means of chronic centrifugation [2].

References

  1. Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase. Paffenholz, R., Bergstrom, R.A., Pasutto, F., Wabnitz, P., Munroe, R.J., Jagla, W., Heinzmann, U., Marquardt, A., Bareiss, A., Laufs, J., Russ, A., Stumm, G., Schimenti, J.C., Bergstrom, D.E. Genes Dev. (2004) [Pubmed]
  2. Neurovestibular modulation of circadian and homeostatic regulation: vestibulohypothalamic connection? Fuller, P.M., Jones, T.A., Jones, S.M., Fuller, C.A. Proc. Natl. Acad. Sci. U.S.A. (2002) [Pubmed]
  3. Vestibular responses to linear acceleration are absent in otoconia-deficient C57BL/6JEi-het mice. Jones, S.M., Erway, L.C., Bergstrom, R.A., Schimenti, J.C., Jones, T.A. Hear. Res. (1999) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities