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Gene Review

FGF11  -  fibroblast growth factor 11

Homo sapiens

Synonyms: FGF-11, FHF-3, FHF3, FLJ16061, Fibroblast growth factor 11, ...
 
 
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Disease relevance of FGF11

 

High impact information on FGF11

  • We have compared the sequences of the nine known mammalian FGFs, FGFs from other vertebrates, and three additional sequences that we extracted from existing databases: two human FGF sequences that we tentatively designated FGF10 and FGF11, and an FGF sequence from Caenorhabditis elegans [2].
  • Chromosomal mapping of two novel human FGF genes, FGF11 and FGF12 [3].
 

Analytical, diagnostic and therapeutic context of FGF11

  • FGF11 was detected at moderate levels by microarray, but not by RT-PCR [4].

References

  1. Comparative genomics on Fgf11 orthologs. Katoh, Y., Katoh, M. Oncol. Rep. (2005) [Pubmed]
  2. Of worms and men: an evolutionary perspective on the fibroblast growth factor (FGF) and FGF receptor families. Coulier, F., Pontarotti, P., Roubin, R., Hartung, H., Goldfarb, M., Birnbaum, D. J. Mol. Evol. (1997) [Pubmed]
  3. Chromosomal mapping of two novel human FGF genes, FGF11 and FGF12. Verdier, A.S., Mattei, M.G., Lovec, H., Hartung, H., Goldfarb, M., Birnbaum, D., Coulier, F. Genomics (1997) [Pubmed]
  4. FGF ligand family mRNA expression profile for mouse preimplantation embryos, early gestation human placenta, and mouse trophoblast stem cells. Zhong, W., Wang, Q.T., Sun, T., Wang, F., Liu, J., Leach, R., Johnson, A., Puscheck, E.E., Rappolee, D.A. Mol. Reprod. Dev. (2006) [Pubmed]
 
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