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Gene Review

PDZRN3  -  PDZ domain containing ring finger 3

Homo sapiens

Synonyms: E3 ubiquitin-protein ligase PDZRN3, KIAA1095, LNX3, Ligand of Numb protein X 3, PDZ domain-containing RING finger protein 3, ...
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Disease relevance of PDZRN3

  • Downregulated genes in USPC included SEMACAP3, ras homolog gene family, member I (ARHI), and differentially downregulated in ovarian carcinoma gene 1 [1].

High impact information on PDZRN3


Biological context of PDZRN3


  1. Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy. Santin, A.D., Zhan, F., Cane', S., Bellone, S., Palmieri, M., Thomas, M., Burnett, A., Roman, J.J., Cannon, M.J., Shaughnessy, J., Pecorelli, S. Br. J. Cancer (2005) [Pubmed]
  2. PDZRN3 (LNX3, SEMCAP3) is required for the differentiation of C2C12 myoblasts into myotubes. Ko, J.A., Kimura, Y., Matsuura, K., Yamamoto, H., Gondo, T., Inui, M. J. Cell. Sci. (2006) [Pubmed]
  3. Identification and characterization of PDZRN3 and PDZRN4 genes in silico. Katoh, M., Katoh, M. Int. J. Mol. Med. (2004) [Pubmed]
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