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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ZNF292  -  zinc finger protein 292

Homo sapiens

Synonyms: KIAA0530, Nbla00365, ZFP292, ZN-16, Zinc finger protein 292, ...
 
 
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High impact information on ZNF292

  • The predicted 1914 amino acid Rlf protein contains sixteen widely spaced zinc finger motifs, and is related to the Zn-15 transcription factor [1].
  • This region contains two Pit-1 bindings sites as well as a Zn-15 binding site [2].
  • A zinc finger transcription factor, Zn-15, is responsible with pit-1 for synergistic activation of the GH gene [3].
  • Optimal concentrations for thymidine incorporation (TI) in both cell populations were Fe and Zn 15 microM and Cu 5 microM; for T cells Ca 2 mM and Mg 4 mM; for B cells Ca 4 mM and Mg 6 mM [4].

References

  1. The rearranged L-myc fusion gene (RLF) encodes a Zn-15 related zinc finger protein. Mäkelä, T.P., Hellsten, E., Vesa, J., Hirvonen, H., Palotie, A., Peltonen, L., Alitalo, K. Oncogene (1995) [Pubmed]
  2. Transcriptional activation of the human growth hormone gene by ras oncogene. Petersenn, S., Maaser, C., Schulte, H.M. Mol. Cell. Endocrinol. (1997) [Pubmed]
  3. The molecular basis of hypopituitarism. Radovick, S., Cohen, L.E., Wondisford, F.E. Horm. Res. (1998) [Pubmed]
  4. Effects of iron, copper, zinc, calcium, and magnesium on human lymphocytes in culture. Carpentieri, U., Myers, J., Daeschner, C.W., Haggard, M.E. Biological trace element research. (1988) [Pubmed]
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