Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Gmcl1 - germ cell-less homolog 1 (Drosophila)

Mus musculus

Synonyms: 2810049L19Rik, DIP, DP-interacting protein, Gcl, Gcl1, ...

Liebe, B. et al., Giordano, G. et al., Leatherman, J.L. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of Gmcl1

GSH ethyl ester decreased, whereas the Gcl inhibitor buthionine sulfoximine increased DomA toxicity [1].

High impact information on Gmcl1

Mice defective in spermiogenesis (Tnp1(-/-), Gmcl1(-/-), Asm(-/-)) showed wild-type mid-preleptotene and bouquet frequencies [2].
Like Drosophila Gcl, mGcl-1 localizes to the nuclear envelope [3].

References

Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency. Giordano, G., White, C.C., McConnachie, L.A., Fernandez, C., Kavanagh, T.J., Costa, L.G. Mol. Pharmacol. (2006) [Pubmed]
Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages. Liebe, B., Petukhova, G., Barchi, M., Bellani, M., Braselmann, H., Nakano, T., Pandita, T.K., Jasin, M., Fornace, A., Meistrich, M.L., Baarends, W.M., Schimenti, J., de Lange, T., Keeney, S., Camerini-Otero, R.D., Scherthan, H. Exp. Cell Res. (2006) [Pubmed]
Identification of a mouse germ cell-less homologue with conserved activity in Drosophila. Leatherman, J.L., Kaestner, K.H., Jongens, T.A. Mech. Dev. (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP011686	Anopheles gambiae str. PEST
GMCL1	Bos taurus
gcl-1	Caenorhabditis elegans
GMCL1	Canis lupus familiaris
gmcl1	Danio rerio
gcl	Drosophila melanogaster
GMCL1	Gallus gallus
GMCL1	Homo sapiens
GMCL1	Macaca mulatta
LOC738528	Pan troglodytes
Gmcl1	Rattus norvegicus
gmcl1	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.