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Eef1a2  -  eukaryotic translation elongation factor 1...

Rattus norvegicus

Synonyms: EF-1-alpha-2, Eef1al, Elongation factor 1-alpha 2, Eukaryotic elongation factor 1 A-2, Ps10, ...
 
 
 
 
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High impact information on Eef1a2

  • Since switching from eEF1A-1 to eEF1A-2/S1 is an indicator that terminal differentiated is completed, the failure of eEF1A-1 to return to basal level may be indicative of the persistence of an unstable tissue environment that includes muscle fiber atrophy, degeneration and neomyogenesis [1].
  • PURPOSE: This study was designed to determine whether the quantitative relationship between the levels of the eEF1A-1(developmental) and eEF1A-2/S1 (adult) isoforms of peptide elongation factor remains stable after denervation of skeletal muscle or whether in response to denervation the relative amount of the developmental form would increase [1].
 

Other interactions of Eef1a2

  • RESULTS: By one month after denervation, relative levels of eEF1A-1 rose dramatically in relation to those of eEF1A-2/S1, and they remained high throughout the remainder of the 25-month denervation period [1].

References

  1. Changes in protein levels of elongation factors, eEF1A-1 and eEF1A-2/S1, in long-term denervated rat muscle. Khalyfa, A., Carlson, B.M., Dedkov, E.I., Wang, E. Restorative neurology and neuroscience. (2003) [Pubmed]
 
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