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Gene Review

ssp1  -  serine/threonine protein kinase Ssp1

Schizosaccharomyces pombe 972h-

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High impact information on ssp1

  • Nucleotide sequence determination showed that ssp1+ encodes a novel protein kinase [1].
  • The ssp1 gene encodes a protein kinase involved in alteration of cell polarity in Schizosaccharomyces pombe. ssp1 deletion causes stress sensitivity, reminiscent of defects in the stress-activated MAP kinase, Spc1; however, the two protein kinases do not act through the same pathway [2].
  • The ssp1 deletion mutant exhibited monopolar actin distribution, but new end take-off (NETO) could be induced in these cells by exposure to KCl or to latrunculin A pulse treatment [2].

Analytical, diagnostic and therapeutic context of ssp1


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