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Gene Review

azr1  -  serine/threonine protein phosphatase Azr1

Schizosaccharomyces pombe 972h-

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High impact information on azr1

  • We also report the sequence of the putative fission yeast cytidine deaminase gene, designated pcd1+, which lies immediately adjacent to azr1+ but which plays only a moderate role in suppression of 5-azaC sensitivity [1].
  • The azr1+ gene is not essential and the null mutant shows no alteration in either DNA repair or checkpoint properties [1].
  • Here we describe the isolation of azr1+, as a multi-copy suppressor of the 5-azaC sensitivity of G2 checkpoint and DNA repair-deficient strains. azr1+ encodes a putative 25 kDa protein with limited homology to a Saccharomyces cerevisiae open reading frame of unknown function [1].


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