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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ade3  -  phosphoribosylformylglycinamidine synthase...

Schizosaccharomyces pombe 972h-

 
 
 
 
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High impact information on ade3

  • The assignment of the known ade genes to steps in purine biosynthesis in Schizosaccharomyces pombe has been completed with the demonstration that an ade3 mutants lacks FGAR amidotransferase, ade1A mutants lack GAR synthetase and ade1B mutants lack AIR synthetase [1].
  • A recessive mutant allele, mef1-84, of a novel locus mapping on the left arm of chromosome I, between ade3 and ura1, 5 cM apart from lys5, confers temperature-sensitive growth and mating deficiency at the non-restrictive temperatures for growth [2].

References

  1. The product of the ade1: gene in Schizosaccharomyces pombe: a bifunctional enzyme catalysing two distinct steps in purine biosynthesis. Fluri, R., Coddington, A., Flury, U. Mol. Gen. Genet. (1976) [Pubmed]
  2. A mating deficient and temperature-sensitive lethal mutant of Schizosaccharomyces pombe defines a new fertility locus. Rusu, M. Curr. Genet. (1992) [Pubmed]
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