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TMEM59L  -  transmembrane protein 59-like

Homo sapiens

Synonyms: BSMAP, Brain-specific membrane-anchored protein, C19orf4, Transmembrane protein 59-like
 
 
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High impact information on TMEM59L

  • BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12 [1].
  • Genomic sequence analysis revealed that the gene encoding BSMAP consists of eight exons spanning approximately 8 kb and lies 6 kb away from the gene encoding CLF-1 in a reverse orientation [1].
  • Using the sequence of cosmids derived from chromosome 19p12, we have identified a gene encoding a novel protein, BSMAP (brain-specific membrane-anchored protein) and cloned cDNA encoding the full-length open reading frame [1].
  • BSMAP has a putative transmembrane domain and is predicted to be a type-I membrane glycoprotein [1].
 

Analytical, diagnostic and therapeutic context of TMEM59L

  • Northern blot analysis revealed that BSMAP mRNA is preferentially expressed at a high level in the brain [1].

References

  1. BSMAP, a novel protein expressed specifically in the brain whose gene is localized on chromosome 19p12. Elson, G.C., de Coignac, A.B., Aubry, J.P., Delneste, Y., Magistrelli, G., Holzwarth, J., Bonnefoy, J.Y., Gauchat, J.F. Biochem. Biophys. Res. Commun. (1999) [Pubmed]
 
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