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Gene Review

FETUB  -  fetuin B

Homo sapiens

Synonyms: 16G2, Fetuin-B, Fetuin-like protein IRL685, Gugu, IRL685
 
 
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Disease relevance of FETUB

 

High impact information on FETUB

  • Yet, fetuin-A and fetuin-B exhibit significant differences at the amino acid sequence level, notably including variations with respect to the archetypal fetuin-specific signature [2].
  • On grounds of domain homology, overall conservation of cysteine residues and chromosomal assignments of the corresponding genes in these species, fetuin-B is unambiguously a paralogue of fetuin-A [2].
  • Five positive colonies that interacted with whole-X protein were obtained and sequenced; namely, fetuin B, UDP glycosyltransferase 1 family-polypeptide A9, mannose-P-dolichol utilization defect 1, fibrinogen-B beta polypeptide, transmembrane 4 superfamily member 4-CD81 (TM4SF4) [3].
  • Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity [1].

References

  1. Identification of Fetuin-B as a member of a cystatin-like gene family on mouse chromosome 16 with tumor suppressor activity. Hsu, S.J., Nagase, H., Balmain, A. Genome (2004) [Pubmed]
  2. Fetuin-B, a second member of the fetuin family in mammals. Olivier, E., Soury, E., Ruminy, P., Husson, A., Parmentier, F., Daveau, M., Salier, J.P. Biochem. J. (2000) [Pubmed]
  3. Molecular epidemiological study on pre-X region of hepatitis B virus and identification of hepatocyte proteins interacting with whole-X protein by yeast two-hybrid. Yang, Q., Cheng, J., Dong, J., Zhang, J., Zhang, S.L. World J. Gastroenterol. (2005) [Pubmed]
 
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