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Gene Review:

Zfp275 - zinc finger protein 275

Mus musculus

Synonyms: 5430431L06Rik, AI593314, DXBay20, DXHXS52, DXPas8

Faust, C.J. et al., Faust, C.J. et al., Avner, P. et al.

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High impact information on Zfp275

Similarly, it is now clear that the T(X;16)16H X-autosome translocation breakpoint lies distal to the DXPas8 (St14-1) locus, narrowing the X-chromosome breakpoint down to a region flanked proximally by this marker and representing, as expected from previous data, the distal quarter of the Hprt-Ta subchromosomal span [1].
However, employing pulsed-field gel electrophoresis and genetic pedigree analysis of interspecific backcross progeny, we have found close linkage of a clone encoding a mouse homolog for human factor VIII-associated gene A (F8A) to DXPas8, thus revealing the first exception to conserved gene order between murine and human loci in the region [2].
Gabra3 and DXPas8 have been shown to be physically linked within a maximal distance of 1600 kb, DXPas8 and CamL1 within 750 kb, and CamL1 and Rsvp within 450 kb [3].

Biological context of Zfp275

Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28 [3].

Analytical, diagnostic and therapeutic context of Zfp275

Using pulsed-field gel electrophoresis, a 3 million-bp physical map containing the X-linked loci Gabra3, DXPas8, CamL1, and Rsvp has been constructed for a segment of the mouse X chromosome homologous to human Xq28 [3].

References

Characterization of a panel of somatic cell hybrids for regional mapping of the mouse X chromosome. Avner, P., Arnaud, D., Amar, L., Cambrou, J., Winking, H., Russell, L.B. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
Extension of the physical map in the region of the mouse X chromosome homologous to human Xq28 and identification of an exception to conserved linkage. Faust, C.J., Levinson, B., Gitschier, J., Herman, G.E. Genomics (1992) [Pubmed]
Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28. Faust, C.J., Herman, G.E. Genomics (1991) [Pubmed]

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ZNF275	Bos taurus
ZNF275	Canis lupus familiaris
ZNF275	Homo sapiens
ZNF275	Macaca mulatta
ZNF275	Pan troglodytes
Zfp275	Rattus norvegicus

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