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Gene Review

GAA  -  glucosidase, alpha; acid

Bos taurus

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High impact information on GAA

  • These glutamic acid residues are coded for by both GAA and GAG [1].
  • After GAA treatment the spermatozoa show severe morphological damage on the membrane system, on the acrosomal complex and on the tubular complex of the end piece [2].
  • The working mechanism of GAA can be assumed to be inactivation of enzyme activities or in direct reactions with plasma membrane material [2].


  1. Isolation and characterization of a cDNA coding for human factor IX. Kurachi, K., Davie, E.W. Proc. Natl. Acad. Sci. U.S.A. (1982) [Pubmed]
  2. Effect of gossypol on bull spermatozoa in vitro. Rovan, E., Kalla, N.R., Frick, J., Adam, H. Urol. Res. (1984) [Pubmed]
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