Chemical Compound Review:
glutamate (2R)-2-aminopentanedioic acid
Synonyms:
PDGA, D-Glu, D-glutamate, H-D-Glu-OH, Lopac-G-2128, ...
- Autoantibodies to glutamic acid decarboxylase in a patient with stiff-man syndrome, epilepsy, and type I diabetes mellitus. Solimena, M., Folli, F., Denis-Donini, S., Comi, G.C., Pozza, G., De Camilli, P., Vicari, A.M. N. Engl. J. Med. (1988)
- Glutamic acid in spinal-cord gray matter in Friedreich's ataxia. Butterworth, R.F., Giguère, J.F. N. Engl. J. Med. (1982)
- A novel subtype of type 1 diabetes mellitus characterized by a rapid onset and an absence of diabetes-related antibodies. Osaka IDDM Study Group. Imagawa, A., Hanafusa, T., Miyagawa, J., Matsuzawa, Y. N. Engl. J. Med. (2000)
- Diabetes induced by Coxsackie virus: initiation by bystander damage and not molecular mimicry. Horwitz, M.S., Bradley, L.M., Harbertson, J., Krahl, T., Lee, J., Sarvetnick, N. Nat. Med. (1998)
- Cloning of cDNA for the glutamate-binding subunit of an NMDA receptor complex. Kumar, K.N., Tilakaratne, N., Johnson, P.S., Allen, A.E., Michaelis, E.K. Nature (1991)
- Differential hippocampal expression of glutamic acid decarboxylase 65 and 67 messenger RNA in bipolar disorder and schizophrenia. Heckers, S., Stone, D., Walsh, J., Shick, J., Koul, P., Benes, F.M. Arch. Gen. Psychiatry (2002)
- Huntington disease and Tourette syndrome. II. Uptake of glutamic acid and other amino acids by fibroblasts. Comings, D.E., Goetz, I.E., Holden, J., Holtz, J. Am. J. Hum. Genet. (1981)
- Neurochemical alterations in Huntington's chorea: a study of post-mortem brain tissue. Spokes, E.G. Brain (1980)
- The alpha-helical to beta-strand transition in the amino-terminal fragment of the amyloid beta-peptide modulates amyloid formation. Soto, C., Castaño, E.M., Frangione, B., Inestrosa, N.C. J. Biol. Chem. (1995)
- The B cell immune response to an idiotype-inducing peptide epitope can be inhibited by immunodominance of a neighboring epitope. Ju, S.T., Nonogaki, T., Bernatowicz, M.S., Matsueda, G.R. J. Immunol. (1993)
- Molecular basis of celiac disease. Sollid, L.M. Annu. Rev. Immunol. (2000)
- Mutations in the gene encoding the human matrix Gla protein cause Keutel syndrome. Munroe, P.B., Olgunturk, R.O., Fryns, J.P., Van Maldergem, L., Ziereisen, F., Yuksel, B., Gardiner, R.M., Chung, E. Nat. Genet. (1999)
- Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix. Winter, H., Rogers, M.A., Langbein, L., Stevens, H.P., Leigh, I.M., Labrèze, C., Roul, S., Taieb, A., Krieg, T., Schweizer, J. Nat. Genet. (1997)
- Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type. Levy, E., Carman, M.D., Fernandez-Madrid, I.J., Power, M.D., Lieberburg, I., van Duinen, S.G., Bots, G.T., Luyendijk, W., Frangione, B. Science (1990)
- A covalent enzyme-substrate intermediate with saccharide distortion in a mutant T4 lysozyme. Kuroki, R., Weaver, L.H., Matthews, B.W. Science (1993)
- A component of the multisynthetase complex is a multifunctional aminoacyl-tRNA synthetase. Cerini, C., Kerjan, P., Astier, M., Gratecos, D., Mirande, M., Sémériva, M. EMBO J. (1991)
- A subdomain in the transmembrane domain is necessary for p185neu* activation. Cao, H., Bangalore, L., Bormann, B.J., Stern, D.F. EMBO J. (1992)
- Novel anti-brain tumor cytotoxins specific for cancer cells. Debinski, W., Gibo, D.M., Obiri, N.I., Kealiher, A., Puri, R.K. Nat. Biotechnol. (1998)
- A single glutamic acid residue plays a key role in the transcriptional activation function of lambda repressor. Bushman, F.D., Shang, C., Ptashne, M. Cell (1989)
- Additive and independent responses in a single receptor: aspartate and maltose stimuli on the tar protein. Mowbray, S.L., Koshland, D.E. Cell (1987)
- Cytoadherence of knobless Plasmodium falciparum-infected erythrocytes and its inhibition by a human monoclonal antibody. Udomsangpetch, R., Aikawa, M., Berzins, K., Wahlgren, M., Perlmann, P. Nature (1989)
- Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine. Flatau, G., Lemichez, E., Gauthier, M., Chardin, P., Paris, S., Fiorentini, C., Boquet, P. Nature (1997)
- Role of poly(ADP-ribose) formation in DNA repair. Satoh, M.S., Lindahl, T. Nature (1992)
- Brain neurotransmitters in dystonia musculorum deformans. Hornykiewicz, O., Kish, S.J., Becker, L.E., Farley, I., Shannak, K. N. Engl. J. Med. (1986)
- Immunocytochemical localization of glutamic acid decarboxylase in monkey striate cortex. Hendrickson, A.E., Hunt, S.P., Wu, J.Y. Nature (1981)
- Interaction of glutamic-acid-rich proteins with the cGMP signalling pathway in rod photoreceptors. Körschen, H.G., Beyermann, M., Müller, F., Heck, M., Vantler, M., Koch, K.W., Kellner, R., Wolfrum, U., Bode, C., Hofmann, K.P., Kaupp, U.B. Nature (1999)
- Acquired vitamin K-dependent carboxylation deficiency in liver disease. Blanchard, R.A., Furie, B.C., Jorgensen, M., Kruger, S.F., Furie, B. N. Engl. J. Med. (1981)
- Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide. Rojas, J.R., Trievel, R.C., Zhou, J., Mo, Y., Li, X., Berger, S.L., Allis, C.D., Marmorstein, R. Nature (1999)
- Does Paramecium primaurelia use a different genetic code in its macronucleus? Caron, F., Meyer, E. Nature (1985)
- Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. Sukumar, S., Notario, V., Martin-Zanca, D., Barbacid, M. Nature (1983)
- A single amino acid exchange transfers VP16-induced positive control from the Oct-1 to the Oct-2 homeo domain. Lai, J.S., Cleary, M.A., Herr, W. Genes Dev. (1992)
- The AAA+ protein torsinA interacts with a conserved domain present in LAP1 and a novel ER protein. Goodchild, R.E., Dauer, W.T. J. Cell Biol. (2005)
- P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium. Wang, R.A., Mazumdar, A., Vadlamudi, R.K., Kumar, R. EMBO J. (2002)
- A phosphorylation site in Bruton's tyrosine kinase selectively regulates B cell calcium signaling efficiency by altering phospholipase C-gamma activation. Guo, S., Ferl, G.Z., Deora, R., Riedinger, M., Yin, S., Kerwin, J.L., Loo, J.A., Witte, O.N. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Isolation and characterization of a 60-residue intestinal peptide structurally related to the pancreatic secretory type of trypsin inhibitor: influence on insulin secretion. Agerberth, B., Söderling-Barros, J., Jörnvall, H., Chen, Z.W., Ostenson, C.G., Efendić, S., Mutt, V. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Spindle pole body separation in Saccharomyces cerevisiae requires dephosphorylation of the tyrosine 19 residue of Cdc28. Lim, H.H., Goh, P.Y., Surana, U. Mol. Cell. Biol. (1996)
- Autoantibody screening in subacute cerebellar ataxia. Trivedi, R., Mundanthanam, G., Amyes, E., Lang, B., Vincent, A. Lancet (2000)
- Subunit III of cytochrome c oxidase is not involved in proton translocation: a site-directed mutagenesis study. Haltia, T., Saraste, M., Wikström, M. EMBO J. (1991)
- A single base mutation in an I-A alpha-chain gene alters T-cell recognition. Griffith, I.J., Choi, E.M., Glimcher, L.H. Proc. Natl. Acad. Sci. U.S.A. (1987)
- IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus. Lan, M.S., Wasserfall, C., Maclaren, N.K., Notkins, A.L. Proc. Natl. Acad. Sci. U.S.A. (1996)
- L-glutamic acid, a neurotrophic factor for maintenance of acetylcholinesterase and butyrylcholinesterase in the preganglionically denervated superior cervical ganglion of the cat. Koelle, G.B., Sanville, U.J., Thampi, N.S., Wall, S.J. Proc. Natl. Acad. Sci. U.S.A. (1986)