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Gene Review

FTH1  -  ferritin, heavy polypeptide 1

Bos taurus

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High impact information on FTH1

  • The canine ferritin H subunit peptide fragment with amino acid residues 148-155 (NH(2)-GDHVTNLR-COOH) in its C-terminal region was recognized by FBP [1].
  • In a 112-d growth trial, individually fed calves (n = 120; 230 kg) received graded levels of FTH, MBM, 50:50 MBM-FTH (CP basis), or SBM with or without tryptophan (Trp) supplementation [2].
  • Canine liver and spleen ferritin H subunit cDNA clones contained an open reading frame for the same 182-amino acid protein as that reported in canine brain ferritin H subunit cDNA although there were substitutions in the 3'-noncoding regions [3].


  1. Purification and characterization of canine serum ferritin-binding proteins. Orino, K., Uehara, M., Okano, S., Watanabe, K. Biometals (2006) [Pubmed]
  2. Combinations of rendered protein meals for growing calves. Gibb, D.J., Klopfenstein, T.J., Sindt, M.H. J. Anim. Sci. (1992) [Pubmed]
  3. Sequence analysis of canine and equine ferritin H and L subunit cDNAs. Orino, K., Miura, T., Muto, S., Watanabe, K. DNA Seq. (2005) [Pubmed]
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