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CAPN3  -  calpain 3, (p94)

Bos taurus

 
 
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High impact information on CAPN3

  • Bovine CANP3 mapped to bovine chromosome 10, relative position 33.9 CM with linkage to nine markers; LOD scores ranged from 4.89 to 8.61 (order, BMS2349-BL1035-RME25-CANP3-BM6305-BMS86 1-ILSTS053-BMS2742-CA090-BMS529) [1].
  • Ovine CANP3 mapped to chromosome 7, relative position 58 CM, with linkage to only one marker, BMS861 (a bovine microsatellite that has been used in sheep), with no recombination and a LOD score of 5.72 [1].
  • Single nucleotide polymorphisms were used to map the bovine and sheep CANP3 genes in two steps [1].
  • Direct sequencing confirmed open reading frames of 2466 bp for both species, and bovine and sheep CANP3 shared 98.5% identity in their amino acid code [1].
  • These sequences were greater than 88% identical to human, pig, rat and mouse CANP3 nucleotide sequences, and greater than 93% identical for the amino acid code [1].
 

Other interactions of CAPN3

  • For example, little cleavage of the 68 kDa protein by CANP2 and CANP3 was noted whereas 210 kDa and 150 kDa proteins remained largely intact [2].

References

 
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