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Gene Review

COX6A1  -  cytochrome c oxidase subunit VIa...

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High impact information on COX6A1

  • Gamma-globulins can be crosslinked at low concentrations by simultaneous treatment with sodium sulphate and glutaraldehyde (SSG-method) [1].
  • Additional bands of about 50/55 kDa were also detected in lysates of SSG/94 and VERO cells by immunoprecipitation [2].
  • The rabbit anti-GRN antibody bound to structurally related antitumor (1-->6)-branched (1-->3)-beta-D-glucans such as lentinan, schizophyllan and SSG, whereas it did not react with linear (1-->3)-beta-D-glucan, curdlan or GRN-derivatives obtained by periodate-oxidation and Smith degradation [3].
  • The bovine gene for the nuclear-encoded heart/muscle isoform of cytochrome c oxidase subunit VIa (COX6A1) was isolated from a library of bovine genomic DNA in lambda EMBL3 and sequenced [4].
  • Primer extension and ribonuclease protection assays were used to map the 5' ends of COX6A1 transcripts in heart; both methods identified several clusters of transcription initiation sites, indicating that COX6A1 mRNA is heterogeneous at the 5' end [4].


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