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Gene Review

lef-2  -  late expression factor 2

Neodiprion sertifer nucleopolyhedrovirus

 
 
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Disease relevance of lef-2

  • Replication of Orgyia pseudotsugata baculovirus DNA: lef-2 and ie-1 are essential and ie-2, p34, and Op-iap are stimulatory genes [1].
 

High impact information on lef-2

 

Chemical compound and disease context of lef-2

  • The genomic location of the lef-2 genes relative to polyhedrin/granulin and the clade structure of the gene trees suggest that genome organization and gene phylogeny are useful parameters to study the evolutionary history of baculoviruses [3].

References

  1. Replication of Orgyia pseudotsugata baculovirus DNA: lef-2 and ie-1 are essential and ie-2, p34, and Op-iap are stimulatory genes. Ahrens, C.H., Rohrmann, G.F. Virology (1995) [Pubmed]
  2. An Autographa californica nucleopolyhedrovirus lef-2 mutant: consequences for DNA replication and very late gene expression. Merrington, C.L., Kitts, P.A., King, L.A., Possee, R.D. Virology (1996) [Pubmed]
  3. Identification, sequence analysis and phylogeny of the lef-2 gene of Helicoverpa armigera single-nucleocapsid baculovirus. Chen, X., Ijkel, W.F., Dominy, C., de Andrade Zanotto, P.M., Hashimoto, Y., Faktor, O., Hayakawa, T., Wang, C.H., Prekumar, A., Mathavan, S., Krell, P.J., Hu, Z., Vlak, J.M. Virus Res. (1999) [Pubmed]
 
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