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Gene Review

mtx2  -  metaxin 2

Danio rerio

Synonyms: SO:0000704
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High impact information on mtx2

  • We also show that eomes regulates the expression of a zygotic homeobox transcription factor mtx2 [1].
  • The expression of mtx2 was dependent on Wnt signals but not on Nodal signals. mtx1 expression was not regulated by either Wnt or Nodal signals [2].
  • After the late blastula period, mtx2 transcripts were detected in the YSL, and they were restricted to the dorsal YSL by the early gastrula period [2].


  1. T-box gene eomesodermin and the homeobox-containing Mix/Bix gene mtx2 regulate epiboly movements in the zebrafish. Bruce, A.E., Howley, C., Dixon Fox, M., Ho, R.K. Dev. Dyn. (2005) [Pubmed]
  2. Novel mix-family homeobox genes in zebrafish and their differential regulation. Hirata, T., Yamanaka, Y., Ryu, S.L., Shimizu, T., Yabe, T., Hibi, M., Hirano, T. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
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