Gene Review:
Abi2 - abl-interactor 2
Rattus norvegicus
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High impact information on Abi2
- These studies demonstrate that THRP and Abi-2 have distinct tissue distribution and distinct biological properties [1].
- Very low levels of Abi-2 mRNA, but not THRP mRNA, were also found in the heart and small intestine [1].
- The thyroid hormone-responsive protein (THRP) is expressed in rat cerebral tissue and has 83% overall sequence homology with c-Abl interactor protein, Abi-2, which is a substrate for the tyrosine kinase activity of c-Abl [1].
References
- Partial characterization of a cerebral thyroid hormone-responsive protein. Haas, M.J., Li, J.P., Pun, K., Mooradian, A.D. Arch. Biochem. Biophys. (2002) [Pubmed]
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