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Gene Review

IGLV2-18  -  immunoglobulin lambda variable 2-18

Homo sapiens

Synonyms: IGLV218, V1-5
 
 
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Disease relevance of IGLV2-18

  • A transient ST-segment elevation associated with chest pain was observed in V1-5 leads, but normal coronary angiograms during ST-segment elevation were observed in every case [1].
  • Master's two step exercise test for pre-operative check-up revealed significant ST elevation in leads V1-5, negative U waves in leads V3-5 and fascicular blocks with retrosternal anginal chest pain [2].
 

High impact information on IGLV2-18

  • When vaginal abnormality (VCUAM V1-5) alone was taken into consideration, an associated developmental disturbance in the renal tract was found in 30% of cases (n = 32 from 107) [3].

References

  1. Inappropriate microvascular constriction produced transient ST-segment elevation in patients with syndrome X. Murakami, H., Urabe, K., Nishimura, M. J. Am. Coll. Cardiol. (1998) [Pubmed]
  2. Intermittent anterior divisional block and far advanced right bundle branch block induced by vasospasm during exercise testing. Kanemoto, N., Kawai, K., Hosokawa, J., Tagawa, R., Goto, Y. Jpn. Circ. J. (1992) [Pubmed]
  3. Female genital malformations and their associated abnormalities. Oppelt, P., von Have, M., Paulsen, M., Strissel, P.L., Strick, R., Brucker, S., Wallwiener, D., Beckmann, M.W. Fertil. Steril. (2007) [Pubmed]
 
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