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Chemical Compound Review

Curantil     2-[[4-(bis(2- hydroxyethyl)amino)-2,7- bis(1...

Synonyms: Curantyl, Kurantil, Persantin, Miosen, Persantine, ...
 
 
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Disease relevance of Persantin

 

Psychiatry related information on Persantin

  • The prognosis for return to work was influenced, in order of predictive value, by the length of preoperative unemployment, type of physical activity in preoperative occupation, noncardiovascular illness, education, anginal class and duration of symptoms [6].
  • OBJECTIVES: The purpose of this study was to test whether cutaneous thermal pain thresholds are related to anginal pain perception [7].
  • Lack of efficacy of the adenosine reuptake inhibitor dipyridamole in the treatment of anxiety disorders [8].
  • In view of associated findings that marijuana smoking decreased myocardial oxygen delivery, decreased exercise time until the onset of anginal pain, and increased myocardial oxygen demand in anginal patients, the use of marijuana by such patients is clearly inadvisable [9].
  • Clinical decision making: dipyridamole thallium imaging [10].
 

High impact information on Persantin

 

Chemical compound and disease context of Persantin

 

Biological context of Persantin

 

Anatomical context of Persantin

 

Associations of Persantin with other chemical compounds

 

Gene context of Persantin

 

Analytical, diagnostic and therapeutic context of Persantin

References

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  2. Evidence of impaired endothelium-dependent coronary vasodilatation in patients with angina pectoris and normal coronary angiograms. Egashira, K., Inou, T., Hirooka, Y., Yamada, A., Urabe, Y., Takeshita, A. N. Engl. J. Med. (1993) [Pubmed]
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  4. Membranoproliferative glomerulonephritis. A prospective clinical trial of platelet-inhibitor therapy. Donadio, J.V., Anderson, C.F., Mitchell, J.C., Holley, K.E., Ilstrup, D.M., Fuster, V., Chesebro, J.H. N. Engl. J. Med. (1984) [Pubmed]
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  7. Low hot pain threshold predicts shorter time to exercise-induced angina: results from the psychophysiological investigations of myocardial ischemia (PIMI) study. Sheps, D.S., McMahon, R.P., Light, K.C., Maixner, W., Pepine, C.J., Cohen, J.D., Goldberg, A.D., Bonsall, R., Carney, R., Stone, P.H., Sheffield, D., Kaufmann, P.G. J. Am. Coll. Cardiol. (1999) [Pubmed]
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  9. Effect of marijuana and placebo-marijuana smoking on psychological state and on psychophysiological cardiovascular functioning in anginal patients. Gottschalk, L.A., Aronow, W.S., Prakash, R. Biol. Psychiatry (1977) [Pubmed]
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  11. Sex differences in the management of coronary artery disease. Survival and Ventricular Enlargement Investigators. Steingart, R.M., Packer, M., Hamm, P., Coglianese, M.E., Gersh, B., Geltman, E.M., Sollano, J., Katz, S., Moyé, L., Basta, L.L. N. Engl. J. Med. (1991) [Pubmed]
  12. Effect of intravenous streptokinase on left ventricular function and early survival after acute myocardial infarction. White, H.D., Norris, R.M., Brown, M.A., Takayama, M., Maslowski, A., Bass, N.M., Ormiston, J.A., Whitlock, T. N. Engl. J. Med. (1987) [Pubmed]
  13. Coronary angioscopy in patients with unstable angina pectoris. Sherman, C.T., Litvack, F., Grundfest, W., Lee, M., Hickey, A., Chaux, A., Kass, R., Blanche, C., Matloff, J., Morgenstern, L. N. Engl. J. Med. (1986) [Pubmed]
  14. Enhanced plasma beta-thromboglobulin in hypoxemia: effect of dipyridamole. Nenci, G.G., Berrettini, M., Todisco, T., Parise, P. N. Engl. J. Med. (1981) [Pubmed]
  15. Lactate enhances the acid-sensing Na+ channel on ischemia-sensing neurons. Immke, D.C., McCleskey, E.W. Nat. Neurosci. (2001) [Pubmed]
  16. Effects of platelet-modifying drugs on arterial thromboembolism in baboons. Aspirin potentiates the antithrombotic actions of dipyridamole and sulfinpyrazone by mechanism(s) independent of platelet cyclooxygenase inhibition. Hanson, S.R., Harker, L.A., Bjornsson, T.D. J. Clin. Invest. (1985) [Pubmed]
  17. Preserved endothelium-dependent vasodilation at the vasospastic site in patients with variant angina. Egashira, K., Inou, T., Yamada, A., Hirooka, Y., Takeshita, A. J. Clin. Invest. (1992) [Pubmed]
  18. Intravenous prostacyclin in thrombotic thrombocytopenic purpura. Fitzgerald, G.A., Maas, R.L., Stein, R., Oates, J.A., Roberts, L.J. Ann. Intern. Med. (1981) [Pubmed]
  19. 'Esophageal angina' as the cause of chest pain. Davies, H.A., Jones, D.B., Rhodes, J. JAMA (1982) [Pubmed]
  20. Relationship between regional myocardial blood flow and thallium-201 distribution in the presence of coronary artery stenosis and dipyridamole-induced vasodilation. Mays, A.E., Cobb, F.R. J. Clin. Invest. (1984) [Pubmed]
  21. Effect of nitroglycerin and dipyridamole on regional left ventricular blood flow during coronary artery occlusion. Becker, L.C. J. Clin. Invest. (1976) [Pubmed]
  22. Phase I and pharmacokinetic trial of intraperitoneal etoposide in combination with the multidrug-resistance-modulating agent dipyridamole. Isonishi, S., Kirmani, S., Kim, S., Plaxe, S.C., Braly, P.S., McClay, E.F., Howell, S.B. J. Natl. Cancer Inst. (1991) [Pubmed]
  23. A platelet-inhibitor-drug trial in coronary-artery bypass operations: benefit of perioperative dipyridamole and aspirin therapy on early postoperative vein-graft patency. Chesebro, J.H., Clements, I.P., Fuster, V., Elveback, L.R., Smith, H.C., Bardsley, W.T., Frye, R.L., Holmes, D.R., Vlietstra, R.E., Pluth, J.R., Wallace, R.B., Puga, F.J., Orszulak, T.A., Piehler, J.M., Schaff, H.V., Danielson, G.K. N. Engl. J. Med. (1982) [Pubmed]
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  25. Low-molecular weight heparin versus aspirin and dipyridamole after femoropopliteal bypass grafting. Edmondson, R.A., Cohen, A.T., Das, S.K., Wagner, M.B., Kakkar, V.V. Lancet (1994) [Pubmed]
  26. Dipyridamole in successful management of pregnant woman with prosthetic heart valve. Ahmad, R., Rajah, S.M., Mearns, A.J., Deverall, P.B. Lancet (1976) [Pubmed]
  27. Pharmacologic stress imaging. Beller, G.A. JAMA (1991) [Pubmed]
  28. Effect of mopidamol on survival in carcinoma of the lung and colon: final report of Veterans Administration Cooperative Study No. 188. Zacharski, L.R., Moritz, T.E., Baczek, L.A., Rickles, F.R., Edwards, R.L., Forman, W.B., Forcier, R.J., Cornell, C.J., Haakenson, C.M., Ballard, H.S. J. Natl. Cancer Inst. (1988) [Pubmed]
  29. Randomised trial of pentoxifylline versus acetylsalicylic acid plus dipyridamole in preventing transient ischaemic attacks. Herskovits, E., Vazquez, A., Famulari, A., Smud, R., Tamaroff, L., Fraiman, H., Gonzalez, A.M., Vila, J., Matera, V. Lancet (1981) [Pubmed]
  30. Comparison of adenosine, dipyridamole, and dobutamine in stress echocardiography. Martin, T.W., Seaworth, J.F., Johns, J.P., Pupa, L.E., Condos, W.R. Ann. Intern. Med. (1992) [Pubmed]
  31. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. van Aubel, R.A., Smeets, P.H., Peters, J.G., Bindels, R.J., Russel, F.G. J. Am. Soc. Nephrol. (2002) [Pubmed]
  32. Dipyridamole inhibits TGF-beta-induced collagen gene expression in human peritoneal mesothelial cells. Hung, K.Y., Chen, C.T., Huang, J.W., Lee, P.H., Tsai, T.J., Hsieh, B.S. Kidney Int. (2001) [Pubmed]
  33. Dipyridamole inhibits PDGF-stimulated human peritoneal mesothelial cell proliferation. Hung, K.Y., Chen, C.T., Yen, C.J., Lee, P.H., Tsai, T.J., Hsieh, B.S. Kidney Int. (2001) [Pubmed]
  34. Biochemical modulation of 'classical' multidrug resistance by BIBW22BS, a potent derivative of dipyridamole. Jansen, W.J., Pinedo, H.M., Kuiper, C.M., Lincke, C., Bamberger, U., Heckel, A., Boven, E. Ann. Oncol. (1994) [Pubmed]
  35. Acute reaction to dipyridamole during myocardial scintigraphy. Angelides, S., Van der Wall, H., Freedman, S.B. N. Engl. J. Med. (1999) [Pubmed]
  36. Aspirin and dipyridamole in the prevention of restenosis after percutaneous transluminal coronary angioplasty. Schwartz, L., Bourassa, M.G., Lespérance, J., Aldridge, H.E., Kazim, F., Salvatori, V.A., Henderson, M., Bonan, R., David, P.R. N. Engl. J. Med. (1988) [Pubmed]
  37. Prinzmetal's variant angina. Coronary arteriogram and left ventriculogram during angina attack induced by methacholine. Endo, M., Hirosawa, K., Kaneko, N., Hase, K., Inoue, Y. N. Engl. J. Med. (1976) [Pubmed]
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