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Gene Review

ORF66  -  virion protein US10

Equid herpesvirus 1

 
 
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Disease relevance of ORF66

  • The whole EBV genome was also demonstrated in the specimens and found to be in linear virion form [1].
  • The effect of monensin on virion production and protein secretion in pseudorabies virus-infected cells [2].
  • Virion DNA probes from EHV-1, PRV and VZV hybridized to similar regions of the HSV genome, and the use of cloned DNA probes allowed heterologous genomes to be oriented with respect to homologous regions [3].
 

High impact information on ORF66

  • Three intense glycoprotein bands (83K, 78K, and 73.5K) as well as four less intensely labeled glycoproteins were detected in [3H]glucosamine-labeled virion preparations [4].

References

  1. Replication of Epstein-Barr virus within the epithelial cells of oral "hairy" leukoplakia, an AIDS-associated lesion. Greenspan, J.S., Greenspan, D., Lennette, E.T., Abrams, D.I., Conant, M.A., Petersen, V., Freese, U.K. N. Engl. J. Med. (1985) [Pubmed]
  2. The effect of monensin on virion production and protein secretion in pseudorabies virus-infected cells. Kerr, C.L., Pennington, T.H. J. Gen. Virol. (1984) [Pubmed]
  3. Location and orientation of homologous sequences in the genomes of five herpesviruses. Davison, A.J., Wilkie, N.M. J. Gen. Virol. (1983) [Pubmed]
  4. Equine cytomegalovirus: structural proteins of virions and nucleocapsids. Caughman, G.B., Staczek, J., O'Callaghan, D.J. Virology (1984) [Pubmed]
 
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