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Gene Review

NRBP1  -  nuclear receptor binding protein 1

Homo sapiens

Synonyms: BCON3, MADM, MUDPNP, NRBP, Nuclear receptor-binding protein
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Disease relevance of NRBP1


High impact information on NRBP1

  • We further show that NRBP inhibits Jab1-induced phosphorylation of c-Jun and AP-1 activation [2].
  • The features of NRBP predict a function as an adapter protein potentially linking signaling pathways involving nuclear receptors and SH2 domain containing proteins [3].
  • The NRBP mRNA transcript, of approximately 2.4 kb, was ubiquitously expressed in a wide range of normal human tissues and 15 human tumor cell lines [3].
  • Immunocytochemistry showed that NRBP and activated Rac3 co-localized to endomembranes and at the cell periphery in lamellipodia [4].


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