Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

rx2 - retinal homeobox gene 2

Danio rerio

Synonyms: Retinal homeobox protein Rx2, SO:0000704

Chuang, J.C. et al., Kennedy, B.N. et al., Rojas-Muñoz, A. et al.

Rojas-Muñoz, Dahm, Nüsslein-Volhard, Kennedy, Stearns, Smyth, Ramamurthy, van Eeden, Ankoudinova, Raible, Hurley, Brockerhoff,

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High impact information on rx2

Though rx2 is also absent in chk, neither rx2 nor rx1 is required for RPE development [1].
We find that expression of mab21l2, mab21l1 and rx2 are specifically absent in the eye field of chk embryos [2].

Anatomical context of rx2

Zebrafish retinal homeobox genes rx1 and rx2 are expressed exclusively in the optic primordia and then in cone photoreceptors of the differentiated neural retina [3].

References

chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Rojas-Muñoz, A., Dahm, R., Nüsslein-Volhard, C. Dev. Biol. (2005) [Pubmed]
Zebrafish rx3 and mab21l2 are required during eye morphogenesis. Kennedy, B.N., Stearns, G.W., Smyth, V.A., Ramamurthy, V., van Eeden, F., Ankoudinova, I., Raible, D., Hurley, J.B., Brockerhoff, S.E. Dev. Biol. (2004) [Pubmed]
Zebrafish genes rx1 and rx2 help define the region of forebrain that gives rise to retina. Chuang, J.C., Raymond, P.A. Dev. Biol. (2001) [Pubmed]

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