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Gene Review

repB  -  hypothetical protein

Lactococcus lactis subsp. lactis

 
 
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Disease relevance of repB

 

High impact information on repB

  • Upstream of the repB gene, all these plasmids contain a strongly conserved region including a 22 bp sequence tandemly repeated three-and-a-half times, and an A/T-rich region [2].
  • A lactococcal plasmid plus origin and two replication protein-coding regions (repA and repB) were located [1].
 

Biological context of repB

  • The structural organization of the pBL1 replication region was highly similar to other well-known theta-replicating plasmids of lactococci, at both the untranslated (the replication origin) and the translated (repB and orfX) sequences [3].
  • The transcribed inverted repeat sequence between repA and repB could form an attenuator to regulate pFX2 replication [1].

References

  1. Genetic analysis of a lactococcal plasmid replicon. Xu, F.F., Pearce, L.E., Yu, P.L. Mol. Gen. Genet. (1991) [Pubmed]
  2. The majority of lactococcal plasmids carry a highly related replicon. Seegers, J.F., Bron, S., Franke, C.M., Venema, G., Kiewiet, R. Microbiology (Reading, Engl.) (1994) [Pubmed]
  3. Nucleotide sequence and analysis of pBL1, a bacteriocin-producing plasmid from Lactococcus lactis IPLA 972. Sánchez, C., Hernández de Rojas, A., Martínez, B., Argüelles, M.E., Suárez, J.E., Rodríguez, A., Mayo, B. Plasmid (2000) [Pubmed]
 
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